ea0067o52 | Oral Presentations | EYES2019
Szymanska Magdalena
, Manthe Sarah
, Shrestha Ketan
, Girsh Eliezer
, Friedler Shevach
, Meidan Rina
*supported by The Robert H. Smith Faculty of Agriculture, Food and Environment Research, Fund for International Cooperation.Objective: Sirtuin1 (SIRT1), an NAD+-dependent enzyme, affects diverse cellular processes. Yet the reproductive functions of SIRT1 remain unclear. The aim of the study was to reveal the regulation of SIRT1 expression and its roles in human granulosa-lutein cells (hGLCs).Methods: hGLCs were retrieved from women...